Huntington's+Disease

Sarah Darragh Biology 1 Honors Huntington’s disease What Is Huntington’s disease? Huntington’s disease is a genetic disorder that affects the nerves in the brain of a human and cause complications in motor skills, the ability to think, and behavior. This disease also leads to muscle problems. Huntington’s disease was once known as Huntington’s chorea. Huntington’s disease is inherited on the fourth chromosome of either parent. In the fourth chromosome, the CAG sequence in the chromosome is duplicated between fourty to one hundred times. This disease is an autosomal dominant trait. If a person with Huntington’s disease has a child, the child has a fifty percent chance in having Huntington’s disease. If the child ends up not inheriting the disease, he or she broke the line of inheritance. Therefore, their children cannot have Huntington’s disease.
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Clinical Description: __** Huntington’s disease doesn’t usually starts showing a sign until a person is in their late thirties, early fifties. It has many symptoms such as irritability, forgetting things, problems swallowing and eating, loss of muscle control,speech problems and many problems with memory. Huntington’s disease makes its victim miserable. In the early stages of this disease, the victim will usually be depressed, where as in the later stage the victim ids helpless and in pain constantly. If I had to describe Huntington’s disease to someone that had no clue what it was I wound tell them that Huntington’s disease is a horrible disease that affects a person in their middle ages and affects their nerves in the brain, that causes them to loss speaking skills, muscle control, and memory. A person with Huntington’s disease does not show signs of having this disease externally until its later stages. In its later stages, a victim is usually confined to a wheelchair because of muscle weakness, and their limbs will eventually starts going whichever way they choose.You can also notice that their speech is becoming harder to understand, Internally this disease is destroying the victim’s brain nerves. Their muscles are weakling as well. As speaking in a biochemically way, Huntington’s disease has an abnormal metabolism affect on the victim. Physiologically, Huntington’s disease causes the victim to undergo memory loss. Huntington’s disease is not curable, therefore the only treatment us medicine to reduce pain caused by the symptoms’. Tetrabenazine is a drug that controls the jerkiness of movements. Tranquillizers are also prescribed to control the movement but also the violent outburst of the victims. There are also medicines to help with the depression of the victims. Also many therapies are used to help with symptoms such as speech, and limb movement. Yes, Huntington’s disease can be detected before signs are shown. The most common three are prenatal testing, pre-symptomatic testing, and confirmatory testing. In prenatal testing, doctors retrieving cells from the amniotic sac. During pre-symptomatic testing, doctors will be able to tell you if you have the disease only if one of your parents is suffering from it. Finally, in confirmatory testing, doctors will be able to determine if the patient that is possibly showing signs of Huntington’s disease really has it or not. [] [] [] [] [] [] [] []
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